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We propose an agent based model to analyse this, and to enable generalisations to be made from the historical data set.
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The results indicate that both models capture certain aspects of the in vitro situation, and at the same time underline the importance of the microenvironment and local intercellular interactions that may be related to phenotypic switching.We have designed a simple agent-based model to analyse the possible outcomes of the "extrinsic" and the "intrinsic" mechanisms of phenotypic differentiation.
To validate its efficiency and reliability, the macro-element based model is employed to analyse a 1/20 scaled-down model of a 25-storey steel concrete composite high-rise building subjected to simulated earthquakes with various intensities through a shaking table.
Parametric studies are conducted based on the detailed FE model to analyse the damage and load demands associated with two major failure mechanisms in concrete crosstie and fastening system, namely the tensile-cracking failure of concrete crosstie and the damage of fastening system.
Finite-element based models are developed to analyse the operation of the devices and to optimize the sensor structure.
In the current state-of-the-art, computational fluid dynamics (CFD) analysis and Blade Element Momentum (BEM) based models are used to analyse and design a wind turbine blade.
Based on the results, it is demonstrated that proposed DEM based model can potentially be used to analyse fluid flow through complex reservoirs.
Appropriate interaction terms were added individually to the base model to give three separate analyses; none of the interaction terms significantly improved the model fit, providing no evidence for substantial subgroup effects.
Our results have established that outputs from process based models and transcriptomics analyses can help to link mechanisms of action of toxic chemicals with resulting demographic effects.
In this view, a DEM based numerical model is proposed to analyse the fluid flow through reservoir's porous media with complex characteristics, especially in the case of existence of natural fractures, hydraulic fractures and interaction of hydraulic and natural fractures for any condition of fluid flow.
The model simulations also provided the base to analyse the cumulative effects caused by the habitat degradation that can ultimately lead to the extinction of local populations.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com