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Additional sequence-based methods for ascertaining gene expression, including massively parallel signature sequencing (MPSS) and serial analysis of gene expression (SAGE), have provided evidence for approximately 450 additional expressed genes that were previously annotated as hypothetical proteins due to lack of sequence evidence of expression [ 23, 24].
In the FEBS Letters paper, we have clearly stated in the abstract that "We present here a fast molecular dynamics based method for determining the mechanisms of functional loss caused by mutations, and attributes to ascertain whether a mutation causes ALS", rather than highlighting the rare mutations.
The results are discussed with reference to the potential of these PCR methods for ascertaining strain dominance and starter fitness in dairy processes.
The methods for ascertaining radiographic hip osteoarthritis are described elsewhere.
Finally, differing methods for ascertaining retinopathy would have an impact on the reported incidence (16– 16).
More readily available alternative methods for ascertaining hypoxic fraction are currently being developed.
Informed consent procedures and protocols for examinations were approved by the Joslin institutional review board, as were methods for ascertaining dates of onset of ESRD and death.
We were also unable to directly ascertain HP1E localization to specific heterochromatin loci using chromatin immunoprecipitation based methods (e.g., ChIP-seq).
The paper presents artificial neural networks (ANNs) based methodology for ascertaining the structural parameters of water harvesting structures (WHS) at the conceptual stage of design.
Several techniques have been proposed that attempt to filter out paralogs; but it was difficult to both define and ascertain the level of consistency that these filtering techniques would have with the original clustering based methods.
This paper presents a method for ascertaining the relevance of inputs in vision-based tasks by exploiting temporal coherence and predictability.
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