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Window based methods due to their processing mode are disadvantaged for small sizes of HTs and begin to be efficient only for medium sizes.
The authors address the issues raised regarding the previous version of the manuscript (although I would consider elaborating more about sequencing based methods due to their impact on the field).
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According to [ 36], the confounding effect of bands that correspond to restricted repetitive elements, and the differences in fragment size caused by insertions/deletions of a few bases are likely to be more neutral in agarose fingerprinting than in sequencer-based methods, due to the larger size of the analysed fragments.
Geometric-based feature extraction is often considered more difficult to implement than appearance-based methods due to the variability in the size and shape of features across emotions [3].
Between the proposed methods, the RPD-based method scored slightly higher than the IPD-based method for 'horn60.' For 'horn60', the IPD-based method showed a slightly poorer quality than both the conventional and RPD-based methods due to the phase-reversal problem addressed in Section 3.
Although EDI-based methods needed more time than LFI-based methods due to requiring many operations to estimate the edge direction, the EDI-based methods provided high-quality results and the LFI-based methods suffered from jagged edge artifacts in the diagonal edge regions.
One of these was Thermoplasma acidophilum TA0175 (PDB 1l6r, chain A), a hypothetical protein that had not been annotated by sequence-based methods due to low sequence identity to homologs [12].
Accordingly, MS-based methods have come into prominence compared with antibody-based methods due to their higher specificity, good reproducibility and precision, and ability to rapidly analyze hundreds of peptide transitions in a single assay.
Although, currently, parentage control in cattle is mainly done by STR-typing, in the near future it will be replaced by SNP-based methods due to the availability of SNP genotypes from genomic selection.
The OH based technique has practical advantage when compared to the H-atom based method, primarily due to the fact that the H-atom LIF is a two-photon process.
As a consequence, structural alignment based methods exceeded other methods due to its more efficient and more accurate performance.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com