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The corresponding tissue based methods are only moderately correlated with co-expression based methods.
Consequently such methods, like all energy based methods, are only concerned with finding the lowest muscle activation possible, penalizing large activations and disallowing co-contraction.
These results suggest that the co-expression based methods are only moderately correlated with the corresponding tissue based methods, and although Essien et al.'s method appears to best agree with Liao and Zhang's method, its performance is affected by the size of the reference ortholog set (i.e., number of the nodes in CCNs).
We find that 1) the co-expression based methods are only moderately correlated with the corresponding tissue based methods, 2) the reliability of co-expression based methods is affected by the size of the reference ortholog set, and 3) the corresponding tissue based methods may lose some information for assessing conservation of gene expression.
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For one driving cycle, the total cost of a trained AC based method is only 2.76% higher than that of DP, while saving 88.7% of calculation time than that DP takes.
Mean-field-based methods are only applicable when the correlations between the constituent parts of the system being modelled are weak.
Further experimental studies using other techniques (e. g. pulse- chase immunoprecipitation and GFP- based methods) are needed, not only to confirm protein import into Paulinella photosynthetic entities, but also to clarify how it occurs.
Although informative, discovery based proteomic methods are only semiquantitative, and therefore further quantitative studies to determine accurate protein expression are required for biomarker development.
The PCR based method was not only a useful and more precise diagnostic approach in the identification of ML cases with negative cytology, but also showed to be efficient in determining the species of the parasites.
Contrarily, structure-based computational methods are only limited by the availability of 3D structures, rendering them an important complement to experimental methods.
Except for L. laeta, L. gaucho and an unidentified species (L. sp. GJB-2008), all the sequences obtained by this PCR based method were classified as Class II only.
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