Sentence examples for based method such as from inspiring English sources

The most established approaches [6] for protein function prediction are based on sequence similarity using BLAST [7], sequence motifs such as PROSITE [8], profile methods such as PFAM [9] and PSI-BLAST [7], and structure based method such as FATCAT [10] and ProCAT [10].

A normalized intensity based method, such as Splicing Index [ 12, 13], is more appropriate to avoid this signal bias.

We have applied an HMM based method such as Interpro [ 51] to validate whether any such protein domains were in fact present in the dataset.

It is known that, under the assumption that data is randomly missed, a likelihood based method (such as the mixed effect model) provides unbiased inference regardless of missing data.

Novel software based methods such as molecular modeling, structure-based drug design, structure-based virtual screening, ligand interaction and molecular dynamics are considered to be powerful tool for investigation of pharmacokinetic and pharmacodynamic properties of drug, and structural activity relationship between ligand and its target.

On the other hand, the use of formalisms which do not require hard formalizations of expert knowledge (such as to transform them into probability distributions or algebraic equations) permits to eliminate one of the strongest limitations of classical knowledge-based methods and other prior knowledge based methods (such as bayessian methods or structural equations).

Constraint based methods, such as Flux Balance Analysis (FBA) and Thermodynamics-based flux analysis (TFA), are commonly used to estimate the flow of metabolites through genome-wide metabolic networks, making it possible to identify the ranges of flux values that are consistent with the studied physiological and thermodynamic conditions.

Moreover, poor inter-observer agreement in grading AOSLO images66 can negatively affect the performance of learning based methods such as CNN.

On the other hand, the performance of several network inference based methods, such as Genomica (iterative NI method A) and GENIE3 (direct NI method A), remained relatively stable with decreasing number of samples.

However, most numerical solutions for beam on an elastic foundation are obtained by mesh based methods, such as finite element or finite difference methods.

Gradient based methods, such as Normal Boundary Intersection (NBI), for solving a MOP require solving at least one optimization problem for each solution point.