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Continuous monitoring with a likelihood based method, on the other hand, has the advantages that all available information, including new data, can be used; sample sizes need not be fixed; and decisions can be made at any time without statistical penalty, irrespective of trial design.
This was established using a confidence scoring based method on the number of different data sets in which the interaction was recorded, the number of different types of experiments supported the interactions, and the number of species in which the interaction was discovered (Geisler-Lee et al., 2007).
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rRNA based methods, on the other hand, are not optimal to compare strains [ 18].
In contrast, several genetically based methods based on the identification of the wciN gene or sizes of specific PCR fragments have been reported before [ 2, 7, 10, 6].
The energy based methods build on the approximation of binding potentials or binding energies [16].
Single image based methods rely on the typical characteristics of haze-free images.
Finally, the good performance of the interaction-based method on the training and test datasets suggests that predictions based on the indirect interactions was also quite good, indicating that the entire interaction network involving all the drug compounds and their direct or indirect interactions, as well as their interactions with human proteins determines the side effects of drug compounds.
Although one cannot conclusively claim the predictive superiority of the WNC-based method on the basis of these observations, this analysis provides additional evidence of the potential predictive sensitivity and specificity of this approach.
Table 13 reports the results of our novel DCNs-based method on the six datasets.
Through leave-one-out cross-validation, the overall 11-order success rates by the network-based method on the aforementioned 1,267 seed proteins are listed in Table 2.
We applied a simulation-based method on the pooled data of each protocol.
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