The other available data are based mainly on trials in which patients were not randomized or without control, so robust evidence for the clinical utility of SROM in treating opioid dependence is lacking 24.
These recommendations are based mainly on clinical trials that were very often conducted a decade or more ago, and on the assumption that E. coli would be involved in nearly half of the cases.
The predictions are based mainly on the largest published randomised trial of the intervention.
Finally, our analysis is limited by the fact that it is based mainly on data collected using a single trial.
However, there is emerging concern based mainly on the results of recent clinical trials and some cross-sectional evidence of increased risk of brain dysfunction in those with repeated episodes.
Three precipitant solution screens, for use in combination with the different host lipids, were rationally designed, based mainly on our experience with a similar trialing of DgkA, as outlined below.
A recent Cochrane analysis concluded that there is level 1 evidence to support the efficacy of infliximab in UC based mainly on the ACT-1 and ACT-2 trial results (Lawson et al. 2006).
These will be discussed separately based mainly on the evidence of the large clinical trials cited in Tables 3 to 6. Aggressive titration of insulin to achieve tight glycemic control is hampered by the potential occurrence of hypoglycemic episodes.
Moreover, results are based mainly on single-center studies, and two recent multicenter trials have suggested potential harm of GLN.
However, the results of our meta-analysis are based mainly on smaller, single-center studies, and two recent multicenter trials have suggested potential harm of GLN.
