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The design of wash water delivery systems is currently based largely on trial and error.
Mechanical engineering has evolved from the practice by the mechanic of an art based largely on trial and error to the application by the professional engineer of the scientific method in research, design, and production.
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Clinical care of these patients is complex and the evidence base for intervention programmes to support managing is based largely on trials of interventions for single conditions, which too often exclude patients with multimorbidity.
The clinical care of these patients is complex and the evidence base for managing chronic conditions is based largely on trials of interventions for single conditions, which too often exclude patients with multimorbidity.
That approval was based largely on clinical trial results published in 2010 in Epilepsia and led by Robert Fisher, MD, PhD, professor of neurology at the School of Medicine.
The approval was based largely on a trial in 63 severely ill children and young adults who had a remission rate of 83percentt within three months — a high rate, given that relapsed or treatment-resistant disease is often quickly fatal.
It got provisional approval for Avastin to treat metastatic breast cancer in 2008, based largely on a single trial.
Mr. Garcia was convicted in 1993 at a trial based largely on the testimony of one eyewitness.
Botulinum toxin type A has been licensed for use in chronic migraine in some countries, based largely on two commercially sponsored trials.
From the beginning, it has been a trial based largely on yellowed documents and strained memories.
But all five were convicted in two trials, based largely on their confessions.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com