Prior to initiation of focus groups, all questions were vetted by the clinician investigators, including U.S. based investigators (J.L. and K.A).
One of the patients with increased weight subsequently discontinued the study based on investigator judgment (following patient refusal of investigator's treatment recommendations to control T2DM).
Tumour response was based on investigator tumour measurements (reviewed by the principal investigator) of target and non-target lesions, using computed tomography (CT) or magnetic resonance imaging (MRI).
Subjects were enrolled as a convenience sample based on investigator availability.
At each visit, patients were dispensed up to a 3-month supply of study medication, based on investigator judgment.
Study subjects were a convenience sample based on investigator availability; overall, we enrolled about half of eligible patients.
Moreover, due to its easy and cheap fabrication process, new configurations can be easily fabricated based on investigator requirements.
Itemised costs were based on investigator provided hospital data.
In 51 (22%) trials, the margin was determined merely based on investigator's assumption.
Tumor response was based on investigator assessment.
These data confirm earlier reports based on investigator assessments [ 10– 10].
