A numerical model of the intensity based interrogation was implemented in order to validate the experimental results.
Discovery of neo-antigens relies mainly on prediction-based interrogation of the 'mutanome' using genomic information as input, followed by T-cell screening.
This may be further fortified by accessing essentially all of known biogenic chemotypes, by structure-based interrogation of the over 500,000 fragments that are commercially available.
The network-based interrogation of the proteomics data showed that members of the NF-κB pathway were altered by the peptide IDR-1002.
The study by Osuka and colleagues is limited because of the use of culture-based interrogation of the microflora and because the pH was not specified by region.
The network-based interrogation of the proteomics data indicated that members of the JNK pathways (for example, MAPK8, MAPK8IP1) were modulated by the peptide IDR-1002.
New combined MR-PET approaches for relating function to ligand receptor interactions may elucidate these mechanisms in vivo, adding depth to the PET-based interrogation of the rich biology of the synapse.
Based on the interrogation of the operative, Omar al-Faruq, the government would take "legal steps" in the "next one or two days," Mr. Yudhoyono said.
Based on the interrogation of the Pakistani militant arrested in Mumbai, India was "absolutely certain" that the attacks had been planned and launched in Pakistan.
Based on its interrogation of the Pakistani terrorist arrested during the attack, the GOI is "absolutely certain" that the attacks originated in Pakistan.
A note of caution is warranted because all published data are based on interrogation of immune responses in the blood.
