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Subsequent differentiation of these mixed cultures would fail to generate single pure lineages needed for transplantation, modeling or population based gene expression studies (e.g. RNA-seq).
It is widely believed that the abundant globin transcripts in whole blood are the causative factors for the lowered sensitivity and increased variability in microarray based gene expression studies.
Most of the microarray based gene expression studies focused on identification of differentially regulated 'genes', but not their 'alternatively spliced transcript isoforms'.
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This is the first report of a microarray based gene expression study undertaken in pineapple.
Therefore, we suggest that the application of seriation for the identification of co-expressed genes in tag-based gene expression studies should be explored further.
Increasing sample size is a bottleneck in DNA microarray-based gene expression studies as microarray experiments are time consuming, expensive, noisy and limited to the number of biological samples (particularly, cancer patients).
Microarray-based gene expression studies can be generally grouped into two major categories.
In order to understand the mechanism of iAs toxicity several microarray-based gene expression studies have been conducted [ 3].
2 The biological importance of TNBCs as a distinct disease entity was established through microarray-based gene expression studies showing five distinct subtypes.
To further validate the microarray data, the SeptiCyte Lab signature was applied to all currently available Gene Expression Omnibus (GEO) HGU133 Plus 2.0 GeneChip data derived from human whole blood leucoctye-based gene expression studies.
For instance, microarray-based gene expression studies were conducted on adipose tissues collected from 7- [ 25] and 9- [ 26] wk old broiler chickens to identify genes differentially expressed between fat and lean lines.
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