Sentence examples for based dosing from inspiring English sources

35 After this initial dose optimisation, no additional benefit was observed to continue concentration-based dosing over clinically based dosing throughout the first year.

As a result, evidence based dosing guidelines are lacking.

Theoretically, the use of PK-PD based dosing should result in additional patient benefits beyond those seen with previous versions of the guidelines which did not specify PK-PD basedosingng [ 3].

Although clinical advantages of using software based dosing methods have not been demonstrated, they should be considered preferred for critically ill patients with severe infections [ 74– 76].

In the absence of therapeutic drug monitoring, body-weight based dosing is recommended, with dosing guidance provided for both approaches to inform future treatment.

Carboplatin pharmacokinetics were monitored following initial renal function-based dosing, with dose adjustments implemented based on observed AUC values.

33 Furthermore, a general IGF-based dosing strategy would not preclude also individualizing treatment based upon responsiveness in growth.

One parallel-group trial used different fixed doses based on weight ranges [ 26] while two others used weight-based dosing [ 27, 30].

The likelihood of dose adjustment was not influenced by the method of GFR determination or the dosing equation used to determine initial renal function-based dosing.

Patients from the GXR trials were further selected into the base case analysis cohorts on the basis of their expected body weight-based dosing.

The aim of this study was to systematically evaluate whether non-weight-based dosing (non-WBD) or weight-based dosing (WBD) of vancomycin leads to a higher proportion of patients achieving the pharmacokinetic/pharmacodynamic target.