Sentence examples for based design when the from inspiring English sources

Favorable ligand conformations, resulting from a conformational search, are of key importance also in the ligand based design, when the structural information about the target is scarce or non-existent and therefore the binding hypothesis assuming the key-lock complementarity has to be derived from known ligands sharing a common 3D arrangement of functional groups (pharmacophore) [13, 14].

The problem is also formulated as a control Lyapunov function based feedback design when the Lyapunov function parameters are given, the solution of this problem can be obtained by solving a linear matrix inequality.

Such clinical trials are incredibly difficult to design when the comparison is based on different populations and for different conditions.

Max Perutz paved the way for structure based drug design when he found the solution to phasing x-ray diffraction intensities producing the first three dimensional structure of a protein, hemoglobin.

Numerical based design of geometrical structures is common when studying systems involving heat exchangers, a central component in several fields, such as industrial, vehicle and household systems.

William A. Beachy is president of the Cleveland based design firm Go Media Inc.

In a study designed to determine duration based on when the next injection was scheduled, results indicated the majority of patients treated with abobotulinumtoxinA were reinjected between months 3 and 4. 65 In clinical practice, versus trials, it is likely that those patients seeking retreatment will be influenced by a number of factors, such as appearance and cost.

Tom Aloisio of Johnston, Pennsylvania, built his own rope bed based on a Shaker design when he was a commanding officer in the Union's Fourth Brigade Field Hospital.

This is the most efficient design when there is equipoise concerning the predictive biomarker based clinical benefit ID hypothesis.

Classifier evaluation suggested the importance of considering a number of aspects of experimental design when developing an expression based tool for general use in ecological monitoring and risk assessment, such as the inclusion of multiple experimental runs and high replicate numbers.

So they based their design around the principle that objects only change locations when humans move them.