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We pursued this question in a prospective, population based cohort study, by linking data from population based registries of birth and mortality in Norway, covering 42 years of observation.
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5 However, our study is approximately 100-fold larger than the UKPDS, with almost 5000 incident amputations and more than 8000 cases of recorded blindness in the derivation cohort, and it is 10 times larger than the US hospital based cohort study reported by Zhao et al. 24 Our study is also more recent than the UKPDS, which started almost 40 years ago and ended almost 20 years ago.
15 16 In brief, the Reykjavik Study is a population based cohort study established in 1967 by the Icelandic Heart Association to prospectively study cardiovascular disease in Iceland.
Design Population based cohort study of general practice patients identified by linkage of nationwide registries at the individual level.
Design Population based cohort study using within person analyses to control for confounding by indication.
Aubert, O. et al. Long term outcomes of transplantation using kidneys from expanded criteria donors: prospective, population based cohort study.
Unlicensed and off label prescription of drugs to children: population based cohort study.
Population based cohort study (2000 2008).
Design Register based cohort study.
Design Registry based cohort study.
Design Population based cohort study.
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