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In summary, the data presented here can be considered in light of the recently proposed weight-of-evidence based classification system for identifying individual genes in amplified regions that are selected for during tumour development (Santarius et al, 2010).
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It also emphasizes a justifiable need for replacing current morphology based classification systems of breast cancer by a molecular classification that may be more relevant prognostically [ 7].
We have developed a prototypical chemical ontology using the proposed rules as described above for a structure based classification system.
A research agenda for the DSM-V advocated the "development of a pathophysiologically based classification system".
The Risk, Injury, Failure, Loss, and End-Stage Renal Disease (RIFLE) is a consensus-based classification system for diagnosing acute kidney insufficiency (AKI), based on serum creatinine (SCr) and urine output criteria (RIFLESCr+UO).
Heterogeneity can be explained by the lack of an established evidence-based classification system for documentation and classification of complications in a standardized manner.
To develop a new SNP-based classification system for MTBC, we used our MLSA-based phylogeny to extracted all lineage-defining SNPs (Table S1).
The PlantTribes database contains an objective MCL cluster-based classification system for plant genes and gene families [ 60, 79, 80].
In response to the first question, I did indeed find that your SVM-based classification system for TF targets was reasonable.
These differences in outcomes underscore the heterogeneity of the disease, and the limitation of using a mainly morphology-based classification system for breast cancer [ 3].
The minimum linear dimension is a critical factor in determining the anatomical success rate of hole closure after surgery, and forms the basis for the new international OCT-based classification system for macular holes.
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