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Sheikh (2005) [ 52] described 135 suspected cases of CCHF, based on a five-year hospital based case series in the province of Balochistan in Pakistan.
It is possible that our BN cases, identified from a population-based twin cohort, were different to the clinic-based cases in the previous study.
The final utility values used for the base case in the model are shown in 1.
A commercially used four-coil condenser of an air-cooled water chiller was used as the base case in the tests and analysis.
A fundamental double-stage Rankine cycle system using the single-component working fluid in each stage for liquefied natural gas (LNG) cold exergy recovery is used as a base case in the present paper.
The results obtained for the other parameters are represented for the base-case in the tornado diagram of Figure 4.
In the best case scenario, savings are 3.4 times as high as the base case in the first year following the intervention, and 7.6 times as high thereafter.
The tornado diagram in Figure 3 illustrates the difference from the base case in the lifetime cost per QALY observed for a number of selected sensitivity analyses performed from a NHS perspective.
When PPSV23 vaccine effectiveness for preventing NBPP was assumed to be 10% greater than base case in the first year post-vaccination, the order of preferred vaccination strategies in the economic analysis were maintained but with ICERs reduced.
An overview of the estimates found in the four approaches is shown in Table 4. Based on these different sources and after discussion in the research project group it was decided to use €15/day for a grade 1 and €17/day for a grade 2 pressure ulcer as input values for the base case in the model and +/-5€ for the sensitivity analyses.
In a further deterministic sensitivity analysis, we changed the utilities from the base case in which the mean utility values are used, to reported median values.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com