Sentence examples for based assays show that from inspiring English sources

When heterozygous this polymorphism protects against a range of microbial infections and cell based assays show that the mutation significantly impairs signalling by both TLR2 and TLR4 [30].

The results of the HIV-1 RT kit and in vitro cell based assay showed that eight compounds effectively inhibited HIV-1 replication at 20 320 nM concentrations with minimal cytotoxicity in MT-4 as well as in CEM cells.

These compounds provide new scaffold for the discovery of Topoisomerase I (Top I) inhibitors and target based assay showed that they can obviously inhibited Top I at 100 μM.

Further, cell based assay showed that compounds 4, 5, 8 & 12 are identified as the best compounds of the series (EC50 ranged from 0.09 to 0.8 μg/ml and 0.12 to 1.06 μg/ml) against HIV-1 IIIB and HIV-1 ADA5 strains, respectively.

Cell based assay showed that majority of the compounds were active at micro molar concentrations (1.39-17.39 µM) and the SI value ranged between 10.77-17.39 against lab adapted strains and 5.8 13.91 against primary isolates.

Immunoblotting and complementary DNA analysis suggest expression of a shorter VPS33B transcript, and cell-based assays show that c.1225+5G>C VPS33B mutant retains some ability to interact with VIPAR (and thus partial wild-type function).

Isothermal titration calorimetry and cell-based assays show that restricted chemical diversity does not limit the affinity or specificity of Fab-YADS2, which behaves in a manner comparable to natural antibodies.

To prove this DNA fragments were indeed nuclear matrix dependent fragments we did the PCR based assay, which showed that 10 out of 15 putative S/MARs where actually associated with the nuclear matrix of Giardia.

The results obtained in the present study show that kaolin based assays differ from TF based assays by significantly shorter R and K values as well as significantly higher α and MA values suggesting that kaolin is a more potent activator than diluted human recombinant TF in cats.

However, studies based on hemolysis assays showed that MSNs (MCM-41-type) were innocuous compared to amorphous SiNPs [12].

Cytocompatibility assessment experiments based on various assays showed that the silanised QDs were non-toxic, aqueous soluble and showed stable fluorescence under biological conditions.