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Conclusions: The major advantage of the TaqMan™ based assay was the speed of diagnosis with a result within minutes of completing the PCR (a result within 4 h of receiving the specimen).
A PCR based assay was used to determine the presence of the tnpA and tnpB genes, as well as of cagA, in 360 H. pylori strains isolated from H. pylori infected patients.
These results demonstrate that the new fluorescence-based assay is a useful tool for the discovery of structure activity relationships among mEH inhibitors.
The 3- 4,5-dimethylthazol-2-yl -2,5-diphenyltetrazolium bromide blue-indicator dye (MTT)-based assay is a simple nonradioactive colorimetric assay to measure cell cytotoxicity, proliferation, or viability.
This novel immuno-based assay is a valuable tool in developing composite biomaterials of synthetic and protein-based polymers with the potential to be applied in other fields of research where protein adsorption onto surfaces plays an important role.
The results confirm that the cell-based assay is a valuable tool in toxicology assessments and high-throughput screenings to detect cytotoxicity mediated by cytochrome P450 biotransformation in preclinical drug development.
These results show that the fluorescence-based assay is a valuable tool in the development of sEH inhibitors by revealing structure activity relationships that previously were seen only by using the costly and labor-intensive radioactive tDPPO assay.
These findings suggest that this cell-based assay is a promising tool to identify new anti-influenza drugs.
The sensitivity of the E6/E7 protein-based assay is a concern that needs to be addressed.
A MALDI-TOF MS-based assay is a suitable and cost-effective method for the initial confirmation of carbapenemase production.
Briefly, the HRP2-based assay is a very sensitive and specific measures of P. falciparum growth by quantifying parasite specific biomolecule, HRP2.
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CEO of Professional Science Editing for Scientists @ prosciediting.com