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To investigate the role of (rLuc) GL4.82 in colon cancer, we have employed imaging based approach to characterize the best transfection technique to get a stable transfected colon DLD1 cell line.
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We proposed a profile-based approach to characterize a disease using a binary vector whose elements indicate whether a given function is perturbed based on the enrichment analysis of expression data between normal and tumor tissues.
Araneda and cowokers pursued a ligand-based approach to characterize the rat's I7 OR [9].
Here we employed a protein microarray-based approach to characterize the entire human TF repertoire for their direct binding capacity to a large set of methylated DNA motifs.
For example, Guimerà et al. proposed a module-based approach to characterize the roles of enzymes according to the modular structure of metabolic networks, which is promising for identification of drug targets [ 6].
A recent study [ 15], which used a capture-based approach to characterize DNA methylation levels in 17 iPSCs generated derived from several cell types using the Yamanaka factors, identified 9 genes that they found to harbor aberrant DNA methylation regardless of the parental source used.
We have undertaken an NGS based approach to sequence the C. pictus transcriptome in order to identify and characterize transcripts potentially contributing to the observed medicinal properties.
The organization should seek to move from compliance based approach to a risk based approach.
Human Rights Based Approach to Programming.
We present a cell based system and experimental approach to characterize agonist and antagonist selectivity for ligand-gated ion channels (LGIC) by developing sensor cells stably expressing a Ca2+ permeable LGIC and a genetically encoded Förster (or fluorescence) resonance energy transfer (FRET -based calcium sensor.
This study would provide an effective approach to characterize the oxygen vacancies based defects which cause threshold voltage shifts and enormous gate leakage in modern MOSFET devices.
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