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An experimentally based approach involves the collection of images of the same particles at different tilt angles.
A more reliable, experimentally based approach involves the use of gene-specific 5′ rapid amplification of cDNA ends (RACE) to validate miRNA-target pairs [ 23].
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These in vitro based approaches involve the exposure of the candidate species at different stages of their life-cycle to varying concentrations of potential toxins/drugs for varying times.
When compared to a conventional finite difference based numerical solution on a fixed grid, the solution obtained from the proposed adaptive grid based approach involves a considerable reduction in the required number of grid points for equivalent accuracy.
However, a calculus based approach involving limits would make the article longer than it already is and the results would turn out the same.
Our network based approach involved multidimensional analysis of gene expression, PPI network, and clinical data.
This 'new view', which complements the more traditional component-based approach, involves the integration of biological research with approaches from engineering disciplines and computer science.
This approach involves the emulsion based amplification of individual PCR products and simultaneous, parallel pyrosequencing of DNA strands [ 14].
MethyLight [ 18, 19] is one of the most common PCR based approaches; it involves the bisulfite conversion of DNA followed by real-time quantitative PCR (qPCR) by using primers and hydrolysis probes that are complementary to either the methylated or unmethylated bisulfite-converted DNA sequences.
Another preconcentration approach involves the allocation of sample between acid and base zones [ 10].
Our results are based on a genetic approach involving the generation of conditional met tg mice, in which Met signalling levels is modulated in a temporally and spatially regulated manner.
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