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Our findings accommodate the prevailing BAK activation models as potentially coexisting mechanisms capable of initiating BAK activation, and supports a model based approach for predicting resistance to therapeutically relevant small molecule BH3 mimetics.
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We compare our stringent DDI-based approach to a conventional DDI-based approach for predicting PPIs based on gold standard intra-species PPIs and coherent informative Gene Ontology terms assessment.
We compare our stringent homology-based approach to a conventional homology-based approach for predicting host-pathogen PPIs, based on cellular compartment distribution analysis, disease gene list enrichment analysis, pathway enrichment analysis and functional category enrichment analysis.
QSAR models in drug design, for instance, strongly depend on the selection of variables, these often being selected using HCA; hence, the usual HCA-based approach for predicting molecular properties through QSAR analysis thus may be based on statistically unsound clusters or simply leaving aside more interesting ones.
A new energy-based approach for predicting constant amplitude multiaxial fatigue life is described.
This article proposes a new energy-based approach for predicting seismic demands of steel structures at the near-fault sites by introducing the concept of dissipated hysteretic input energy during largest yield excursion (ΔEh).
In this paper a new copula-based approach for predicting the wave height at a given location by exploiting the spatial dependence of the wave height at nearby locations is proposed.
In this work, we develop a novel homology-based approach for predicting the H. sapiens-M.
In this work, we develop a stringent DDI-based approach for predicting the H. sapiens-M.
In this work we have proposed a stringent homology-based approach for predicting host-pathogen PPIs.
This study proposes a GA-based approach for predicting the O-glycosylation sites in proteins.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com