Two large randomised controlled trials that compared home based and centre based cardiac rehabilitation in the United Kingdom have recently been completed.
19 The one systematic review (of randomised controlled trials) that compared home based and centre based cardiac rehabilitation to date found no significant differences in outcomes, 20 but there were only 750 participants in total and patients with heart failure were excluded.
A total of 16 health economic evaluations were included, of which ten were trial based and six were wholly model based.
This article will discuss several methodological challenges in designing and conducting a pragmatic primary care based randomised controlled trial, based on our experiences in the DIAMOND-study and will discuss the rationale behind the choices we made.
From the beginning, it has been a trial based largely on yellowed documents and strained memories.
Two appetitive conditioning experiments with rats examined time-based and trial-based accounts of the partial reinforcement extinction effect (PREE).
It is interesting to note that C or D improves P and Q in more trials based on M 1 than those based on M 2 or M 3 because M 1 does not take into consideration the confidence radius as weighted means (Table 4(a)).
They did some clinical trials based on this, and it was based on a different prognosis if you have diffuse peritonitis versus a localized infection, and I think that kind of concept would be good to start to apply to different types of infection.
Rather, they will have to be embarrassing show-trials based on torture evidence and coerced confessions.
The present review extends previous work through the inclusion of trials based in community based settings.
This trial was large, population based, and pragmatic.
