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The high dimensional propensity scores based analyses were conducted using stratification, as described.
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Region-of-interest (ROI -based analyses weROI -baseded companalysese cortical thickness of the OFC generated by FreeSurfer based on the Desikan-Killiany atlas [ 20].
Here, JIS-based analyses were conducted in order to characterize the extent to which the pressure to avoid T cell recognition is manifested in genomic differences among representative hit-and-run, hit-and-stay, and commensal bacteria.
In addition to the MHC, the chromosome 19q13 region surrounding the apolipoprotein E (APOE) gene has shown consistent evidence of involvement in MS when family-based analyses were conducted.
Pathway-based analyses were conducted for DNA repair genes; they were not conducted for viral infection and cell entry genes as only select genes were targeted for evaluation and together do not fully represent a pathway.
All network-based analyses were conducted with MetaCore software suite http://www.genego.com.
This is supported by our previous study [ 1] in which pedigree-based analyses were conducted to estimate genetic correlations between mastitis caused by different pathogens.
Design-based analyses were conducted to account for features of the sample design and provide approximately unbiased estimates and appropriate standard errors [ 22, 23].
Anchor-based analyses were conducted by comparing scores on the PRIMUS and U-FIS with published RD values for the EQ-5D [ 34].
Voxel-based analyses were conducted on baseline perfusion images using the spatial smoothing with a three-dimensional isotropic Gaussian kernel size (FWHM; 8 mm).
All codon-based analyses were conducted using the accepted species tree topology (fig. 2), the F3×4 codon frequency model (Goldman and Yang 1994), complete deletion, and three different starting ω values (0.01, 0.1, and 1) to overcome the multiple local optima problem.
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