Sentence examples for base substitutions and specific from inspiring English sources

Of these, 12 were of sufficient size (>400 bp) to potentially yield a significant number of phylogenetically informative base substitutions, and specific primers were designed to maximize read length [the original primers of Mauro-Herrera et al. [22] were designed for short fragments flanking single nucleotide polymorphisms (SNPs)].

Specific base substitutions and other transitions and transversions in the tumor suppressor gene p53 have been associated with PAH exposure [ 17].

Sequence variation included base substitutions and INDELS.

Breast cancer simple somatic mutation data include single base substitutions, multiple base substitutions and short indels.

This included 3884 single base substitutions and 39 indels.

The landscape was investigated also based on the base substitutions and their immediate 5' and 3' nucleotides.

In this study, we use three types of such information: that base changes within two bases of a splice site abolish splicing at that position [ 19], that some base changes close to a splice site may modulate splicing at that position [ 20], and that missense base substitutions affect specific aspects of protein function.

For example, Pols I, III, IV or V were required for base substitutions at specific hotspots.

Most mutations (n = 38) were single-base substitutions, two were two-base substitutions and four were small (1 3 nt) conserved deletions (Table 1).

The BPL method can determine one base substitution by specific hybridization and detect the ratio of methylation to non-methylation.

In addition to environmental factors and intrinsic variations in base substitution rates, specific genome-destabilizing mutations can shape the mutational trajectory of genomes.