Sentence examples for base substitutions and small from inspiring English sources

This approach provides a simple, closed-tube, semi-automated and cost-effective method for detecting base substitutions and small insertions or deletions [15].

Finally, we have highlighted increased frequencies of both base substitutions and small indels in regenerant plants.

Base substitutions and small deletions/insertions were detectable by the CEL1 nuclease assay or HRM analysis.

With these methods single base substitutions and small deletions and insertions can be detected.

Current diagnostic testing uses Sanger sequencing as the gold standard to detect base substitutions and small indels (insertions or deletions).

To detect sequence mutations (e.g., indels, base substitutions, and small inversions), we performed bidirectional exon-resequencing analyses on the APC and MCC genes.

Each mini-IS element differed from others in the same group by some 10 20% in sequence, due to base substitution and small insertion/deletion mutation differences (Fig. S10).

The frequency of base substitution and small deletions including single base deletions and deletions < 1 kb formed in fiber-treated MEF cells was only 2-fold higher than those from nontreated cases.

This mutator phenotype increases the spontaneous rates of base substitution and small insertion/deletion mutations approximately 100 1000-fold (Bhattacharyya et al, 100 1000-foldshleman et al, 1995, 1996) and provides a plausiBhattacharyyaon for thethigh rale of carcinogenesis observed.

Although some cancer genomes probably contain over a million mutations at sufficient frequency to be identified by standard NGS methods, most have tens of thousands of base substitution and small indel mutations.

In a prior study, we showed that G[8,5-Me]T is mutagenic in simian and human embryonic kidney cells, causing a wide variety of mutations at or near the cross-link, which included single- and multiple-base substitutions and small frameshifts.