Sentence examples for base stacking at the from inspiring English sources
The reduced base stacking at the adduct sites may also contribute to the thermal instability.
The reduced base stacking at the adduct sites may also contribute to the thermal destabilization.
The base stacking at the conjugated region together with the W indolyl group is shown in Figure 8.
The interference of the base stacking at the cross-linked region was consistent with the remarkable chemical shift perturbations of the C aromatic protons (17).
Consistent with the B-DNA geometry, the sugar puckers were either C1′- exo, C2′- endo, or O4′- endo. Figure 3C,D displays the base stacking at the cross-linked base pairs.
With regard to deoxyribose pseudorotation, the sugar puckers in the average structure were either C1′- exo, C2′- endo, C3′- exo, or O4′- endo. Figure 3A,B displays the base stacking at the cross-linked base pairs.
At the adducted base pair, the base stacking of the duplex containing cyclic hemiacetal 8 was improved as compared to that of the duplex containing cyclic hemiacetal 10.
DNA base lesions cause structural and chemical changes at the site of damage and inevitably hinder normal base pairing and base stacking in the vicinity, hence leading to general instability and distortion of the DNA double helix.
It may be expected that terminal base stacking would be less stable than base stacking within the chain, thus rendering the terminal phosphodiester bonds easier to break.
Figure 7C,D shows the base stacking and base pairing at the lesion site.
