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The exception was found in the 10 base resolution analysis for C. jejuni, where GenomiPhi and Repli-G exchanged position; while significant, the difference between the Repli-G and GenomiPhi samples in this instance was slight (0.005).
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Single-base resolution analysis of active DNA demethylation using methylase-assisted bisulfite sequencing.
Neri, F. et al. Single-base resolution analysis of 5-formyl and 5-carboxyl cytosine reveals promoter DNA methylation dynamics.
3. Wu, H., et al. Single-base resolution analysis of active DNA demethylation using methylase-assisted bisulfite sequencing.
It will be also useful for base-resolution analysis of 5-hydroxymethylcytosine when applied to genomic DNA treated with adequate oxidants or enzymes.
To ensure that CoBRA digests were representative of high methylation status in tumours, we carried out base-resolution analysis of promoter region methylation for BNC1, CCDC8 and GALNT9 by cloning and sequencing individual bisulfite-modified alleles from select tumours (Additional file 9: Figure S5).
Yu, M. et al. Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome.
Xia, B. et al. Bisulfite-free, base-resolution analysis of 5-formylcytosine at the genome scale.
Linear resolution analysis for synthetic 'hanging' plume input structures in the upper mantle and transition zone.
Nemala, S.K., Zotkin, D.N., Duraiswami, R. & Elhilali, M. Biomimetic multi-resolution analysis for robust speaker recognition.
With this new pipeline, it is now possible to perform whole-genome DNA methylation analysis at single base resolution for a large number of samples for understanding how DNA methylation and its changes are involved in development, differentiation, and disease pathogenesis.
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