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The case of selfing from a F2 base population can be found in the supporting information.
Alternatively, the actual additive and dominance variances, given the observed genotypes in each base population, can be computed and Ve can be adjusted exactly for the base population.
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Our results suggest genetic variation for some traits in base populations can be maximized by using molecular marker information and strategy KIN.
After lowess correction, one population is selected as the center population and all data is shifted such that this population obtains median M equal to 0. Selection of a center population can be based on different assumptions.
The optimal cut-off value within a specific population can be based on a local screening programme, taking major determinants into account, including the incidence of neoplasia, the intended screening interval, colonoscopy capacity and cost efficacy.
Individuals in the population can be ranked based on non-dominated sorting mechanism.
However, when selection intensities differ between schemes, the Bulmer effect can affect the ranking and a comparison based on accuracies in an unselected population can be misleading [ 23].
Segregating sequence differences among individuals in a mapping population can be detected based on the variation of the hybridization signal [ 14].
One possible explanation for this finding is that our study population comprised residents of Al-Ahsa, where the population can be divided based on religious beliefs into two main populations (Sunni and Shiaah) between which intermarriage rarely occurs.
The γδ TCR+ population can be subdivided based on the expression of specific Vγ and Vδ TCR chains [ 1], defined here using the nomenclature of Heilig and Tonegawa [ 2].
Specifically, we examined whether there is an increased risk of PE in the very elderly population; whether the very elderly demonstrate an increased number of PEs; and whether PE diagnoses in the very elderly population can be made based on clinical symptoms, D-dimer values, electrocardiographic changes, blood gas analyses, and radiologic imaging.
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