Sentence examples for base pairing with a from inspiring English sources

Because four strands are available at each end of the G-quadruplex region, the likelihood of occurrence of a single event (base pairing with a strand in another synapsable quadruplex unit) is greatly increased.

Through the imperfect base pairing with a binding site in the 3′ UTR of mRNA, miRNA regulates the expression of the target gene or destabilizes its mRNA [ 10].

The final dicer product is a short fragment of the RNA duplex formed by Watson-Crick base pairing with a two-nucleotide overhang at the 3' end.

Thus, SL2 contains conserved sequences required for base pairing with the majority of the target mRNAs, and SL1 and SL3 are crucial for base pairing with a subset of targets.

Most sRNAs act by base pairing with a target mRNA, modulating its translation and/or stability; many of these RNAs share only limited complementarity to their mRNA target, and require the chaperone Hfq to facilitate base pairing.

The crystal structure of the Rev1 ternary complex revealed that incoming nucleotide selection is dictated by the interaction of dCTP with an Arg324 residue, rather than base pairing with a dG template (46).

The most important requirement for microRNA base pairing with an mRNA target in animal cells is a continuous and perfect complementarity of microRNA nucleotides 2 8, known as the seed region, to the 3' UTR of the target mRNA [19].

Another proposal is that slippage might be initiated by dNTP misinsertion followed by primer relocation to allow complementary base pairing with an adjacent template base (Kunkel & Soni, 1988); this misinsertion primer relocation model is limited to specific sequence contexts.

Implementation of the cSBL approach could potentially increase reads to twenty-three base pairs, or forty-six total base pairs with a mate-paired constructed library.

Primers designed to amplify the CA repeat detect 16 alleles from 121 to 151 base pairs, with a heterozygosity of 0.74.

Under these conditions, it might be more favorable for a (partially) melted duplex region to base pair with a complementary strand in another synapsed quadruplex.