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The damage may lead to incorrect base pairing, resulting in the substitution of bases or the deletion of a base.
MiRNAs bind to the 3' UTR of target mRNA through base pairing, resulting in target mRNA cleavage or translation inhibition [8].
They bind to the 3'UTR of target mRNAs through base pairing, resulting in target mRNAs cleavage or translation inhibition[1], [2], [3].
miRNAs normally function as negative gene regulators at the post-transcriptional level by binding to the 3'UTRs of the target mRNA through base pairing, resulting in its cleavage or translation inhibition [4], [5], [6].
They usually function as the negative regulators for certain genes at the post-transcriptional level by binding to the 3'UTRs of the target mRNAs through base pairing, resulting in the target mRNAs cleavage or translation inhibition [1], [2], [3].
In mammals, miRNA mRNA interactions are most often through imperfect base pairing, resulting in translational repression.
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Removal of the kanr cassette by digestion with NotI and religation leaves 57 base pairs, resulting in an in-frame insertion of the 19-amino-acid EZ linker.
SSCP is the electrophoretic separation of single-stranded nucleic acids based on subtle differences in sequence (often a single base pair), resulting in a different secondary structure and a measurable difference in mobility through a gel.
The resulting secondary structure is then used as a scaffold for additional base pairs, resulting in a planar graph representation.
Doxorubicin intercalates among DNA base pairs resulting in conformational changes in DNA structure and changes in the activity of topoisomerase.
RNAcofold was included here because it considers intramolecular base pairs resulting in lower energies for sequences that are further away from perfect complementarity.
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