Your English writing platform
Discover LudwigSuggestions(5)
Exact(5)
Crispr-Cas9 is able to edit genes at the smallest resolution – down to a single base pair within the sequence of the 3bn bases that make up the human genome.
MicroRNAs (miRNAs) are short, noncoding RNAs that generally base pair within the 3′ untranslated (3′UTR) region of target mRNAs, causing translational inhibition and/or mRNA degradation.
Fine mapping identified the gene underlying this QTL as a Myb transcription factor and association and transformation studies pinpointed the functional nucleotide polymorphism (FNP) to a single base pair within the DNA binding domain of this gene.
Sagawa et al. [ 37] suggested that the specificity of Type II RNases H would be similar to that of a restriction enzyme and that cleavage, and hence amplification, would be completely prevented if there was a mismatch at the RNA DNA base pair within the duplex formed between the primer and the template.
Electrophoretic patterns with a probe corresponding to the DQA1*0501 Y-box sequence, which diverges from the DQA1*0101 Y-box sequence by a single base pair within the highly conserved reverse CCAAT sequence, appear to vary with the cell type, and binding appears weaker than with the DQA1*0101 probe (see Fig. 2).
Similar(55)
Howard was especially curious about how variations of base pairs within the two genes interacted with each other to impact asthma.
However, owing to the dynamical motions of the base pairs within the molecular stack, as well as sequence-dependent inhomogeneities in energetics and base base couplings, DNA charge transport differs considerably from that in solid state π-stacked materials.
Through further regulation of the number of aptamer-involved base pairs within the duplex we can tune not only the signal increase but also the response rate of these synergically stabilized duplex probes to achieve optimal sensor performance.
Although it is not possible to further characterize structural details of this extra mass, our data from the high salt treated sample reveals, at least partially, the location of the precursor sequences of the 17S rRNA, confirming the presence of complementary base pairing within the 5′ end, as well as between the 5′ and 3′ ends in the 17S rRNA precursor.
These strains are designated as TcdA-negative though, regarding serogroup F-strains, mere lacking 1800 base pairs within the repetitive regions [29], [30].
When both number of matched and the nature of mismatched base pairs within the proximal-8 region are taken into account, the number of subclasses for the classes 7, 6 and 5 were found to be 116, 528 and 672, respectively.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com