Sentence examples for base of the mutation from inspiring English sources

Closer examination revealed the mutations which contained a purine as the second base of the mutation lead to a significant increase in virus titre and a reduced amount of splicing.

Both of the study by Liao et al (2012) and Reimers et al (2014) focussed on the effect of aspirin on survival based on the mutation of some biomarkers, such as PIK3CA.

The first step of the algorithm involves assigning each sample to one of two cohorts based on the mutation status of the investigated gene.

They are based on the mutation accumulation theory of half a century ago.

We then calculated the values of D and D* based on the mutation distribution in total and pruned datasets.

Fearon and Vogelstein (1990) first proposed a temporal ordering of mutations based on the mutations in colorectal tumors from different stages.

Within this G-run, the base position of the mutation cannot be defined, and all the InsGs are thus regarded as identical mutations; they will always be counted as one single mutation if occurring in the same animal.

It is proposed that DNA evolution has some very local process which depends on the immediate neighbouring bases, either for the insertion of individual bases or the mutation of individual bases – this would have the effect of magnifying local random strand biases.

Fluorescent signals revealing the nature of the base at the mutation site was detected by fluorescence polarization in a Victor2 (PerkinElmer Wallac).

For simplicity, we present here a single time estimate: that of the TMRCA of 33 chromosomes, based on each of the mutation rates.

Based on the location of the mutation in the DNA code, researchers believe that the mutation prevents a protein called RUNX1 from attaching to the PDCD1 gene.