Sentence examples for base of the binding from inspiring English sources

When mapped onto the three-dimensional fold of Cass2, these side chains, in addition to residues Phe63, Thr64 and Ala66, cluster along a projected surface feature well to the "base" of the binding cleft (depicted in Figure 7A).

This 'transmission switch' includes W6.48 (which interestingly is also located close to the base of the binding pocket of many GPCRs) and also involves L5.51, P5.50 and L3.40.

Identification of platelet activation based on the binding of fibrinogen (activation of glycoprotein IIb-IIIa) did not correlate with BMI.

The anticancer activity of InO is based on the binding of the ADC to CD22-expressing cells followed by internalization of the ADC-CD22 complex and the intracellular release of N-acetyl-γ-calicheamicin DMH via hydrolytic cleavage.

The specificity of detection in immunolabelling is based on the binding of the primary antibody, of which the paratope is typically directed towards short chain fragments of the full-length peptide21.

The method presented here for the in situ detection of mARs is based on the binding of a ligand (FITC-BSA-bound testosterone) on mARs.

This correlation was not apparent when activation of platelets was identified based on the binding of fibrinogen.

from the HA of A(H1N1 pdm09 based on the binding affinities of epitope-MHC II allele complex [ 9].

It was achieved via 10 rounds of directed evolution based on the binding affinity of the A domain with a surrogate intermediate (acyl-adenosine monosulfate).

To further illustrate the difficulty of the current classification task of intrafamily separation, a simple unsupervised classification scheme aimed at predicting the membrane-binding behavior of a domain based on the binding behavior of closely related homologs is fashioned.

Here we present a family of novel photoacoustic contrast agents that are based on the binding of small optical dyes to single-walled carbon nanotubes (SWNT-dye).