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Hence, four-box codon families can have the same base modifications at the wobble position, with different codon reading.
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The common feature of the discrepancy is that the base modification at the wobble position allow broader specificities to promote a functionally redundant decoding system than the codon readings predicted by wobble parsimony.
Pacific Biosciences expects that researchers will use this capability to study a broad range of base modifications at single base resolution.
The τm5s2U anticodon wobble base modification at U34 was modestly down in MERRF (Fig. 3b).
However, DOX, possibly thanks to its structure, also stimulates ROS production, which may induce various DNA damage, first of all oxidative base modifications, especially at moderate DOX concentrations [ 29].
The importance of the endonucleases at the sporophytic stage of seed development could be dependent on their repair function if base modifications are particularly prevalent at that stage.
Modified aptamers were synthesized at the 1 µmol scale on a ABI 3900 DNA synthesizer with some adjustments to the protocol to account for the unique base modifications described herein.
The universal base modification tA occurs at position 37 in a subset of tRNAs decoding ANN codons.
Epigenetic modifications at the Foxp3 locus during Treg differentiation.
140b Another radical SAM involved in the post-translational modification of nucleosides is one that acts in the complex tricyclic base modification of a guanosine at position 37 in tRNA.
One of the mechanisms is anticodon base modification.
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