We calculated the excess odds of disability conferred by individual comorbidities and suboptimally controlled glucose (A1C ≥8%) for each functional group as [ odds ratio [OR]_base − OR_adjusted)/(OR_base − 1)] × 100; where the base model was adjusted for age, sex, race/ethnicity, education, smoking, and diabetes and the adjusted model was also adjusted for individual comorbidities or A1C ≥8%.
The base model was adjusted for age.
In Cox regression models, the base model was adjusted for age and the fully adjusted model for smoking, alcohol intake, physical activity and prevalent cardiovascular disease, metabolic disorders and cancer.
In the second model, the base model was adjusted for study child's gender and age, in the third model maternal characteristics (age when child was born, highest level of education and country of birth) were added and finally in the fourth model the study child's average estimated daily energy intake (MJ), MVPA, total screen time and hours of sleep were added.
Hence, the first (base) model was adjusted for age and sex, the second model additionally for education, marital status, and severity of diseases, and the third model additionally for health behaviors, including leisure-time physical activity, BMI, tobacco, and alcohol, depending on the factor under study.
