For example, sickle-cell anemia is a human genetic disease that results from a single base difference within the coding region for the β-globin section of hemoglobin, causing a single amino acid change that changes hemoglobin's physical properties.
The 28S data revealed two weakly supported clades (28S.I and 28S.II) that differed from each other by 4 8 nucleotide substitutions, while there was a maximum of 2 base differences between wasps within the two clades (Fig. 3).
Based on validated differences within the mTOR pathway and significant changes in cell cycle and TGFβ signaling, alterations in cell size were assessed.
Based on major differences within the hemagglutinin (HA) and neuraminidase (NA) proteins, 16 HA and 9 NA subtypes have been recognized, all of which have been isolated from avian species [ 1- 3].
Mean numbers of base differences between isolates within each fair are shown on the highlighted diagonal; mean numbers of nucleotide differences between groups of isolates recovered from each fair are shown in the area below the diagonal.
Primers were designed that specifically amplify the cDNA of either H2A.Z isoform based on substantial sequence differences within the untranslated regions (UTRs).
Nevertheless, there were 385,789 base differences (excluding unassigned,"N", base calls), within 43,761 unigenes, between the B. rapa-cured (or A genome-cured) and B. oleracea-cured (or C genome-cured) unigene sequences.
To determine whether there were differences within the groups based on the results of the urine cultures, we performed a post hoc outcome analysis stratified on the basis of positive or negative results on urine culture.
This comparison revealed a single base pair (bp) difference within the predicted Fur Box [1] at the −5 position relative to the start of transcription.
The IQV is based on the ratio of the total number of differences in the distribution to the maximum number of possible differences within the same distribution.
