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Three genes contain different single base changes in the first intervening sequence (IVS) 5′ splice site.
We further looked at the number and type of base changes in the RNA-seq data.
Based upon relative magnitudes of structural resource cost parameters, we argue that retail lending becomes considerably less responsive to exogenous monetary base changes in the post-October 2008 regime of positive excess reserves and virtually zero wholesale lending.
Specifically, mutations in the 3' sequence which decrease self-cleavage activity could not be compensated by base changes in the 5' sequence as predicted by these models.
All amino acid substitutions were generated by a one-step reverse cyclic PCR method using the appropriate base changes in the synthetic oligonucleotides [29].
Compensatory base changes in the ITS2 region for Rhizopus species were calculated using the ITS2 Database and the programs 4Sale and CBCAnalyzer [74], [75], [76], [77].
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The bases involved in compensatory base changes in this part of the RNA (Fig. 4) offer support to the predicted folding.
This mutant contained a single base change in the regulatory region upstream of the riboflavin biosynthetic genes.
Before the invention of the base editor, in order to make a single base change in the code (for instance, to change a C to a T), it was necessary to first cut the DNA.
Three recent studies found that people with a single nucleotide base change in the genes that code for cell receptors that bind nicotine--the addictive chemical in cigarettes--were more likely to develop lung cancer (ScienceNOW, 2 April).
The presence of a single base change in the amplicon influences the thermodynamic stability of the duplex resulting in a slight change in the melting temperature (Tm) and the shape of the melt curve [ 14, 15].
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