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In our base case, we used the recommended 3% discount rate [17].
In the base case, we used mean estimates for both vaccine efficacy and calibration values.
In the base case we used the "adjusted treatment" received estimate of the treatment efficacy.
In the base case we used a time horizon of 3 years since it was the longest period over which results were stable, with acceptable precision.
In the base case, we used a cost per hospitalisation that was equal in both arms due to small number of observations.
For the base case, we used 3.7% for both discount rates, which is in line with the recommendation of the working group on discount rates in health economic analysis lead by the National Health Fund.
Similar(51)
So in the base-case we used the lowest reported value of revision incidence for ACLR.
In the Base Case analysis, we used the effectiveness data reported by NICE.
In the base case analysis, we used an HR.DM of 1.33 for EFS and an f.DM of 54%.
In the base case analysis, we used an HR.DM (HR for "disease" among DM patients receiving tamoxifen) of 1.29 and an f.DM of 0.54.
Thus, in the base case analysis, we used the weighted average cost of CMF, AC and TAC.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com