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Sensitivity analyses will be conducted by testing a 20% range versus base case values for cost parameters and effectiveness measures, as well as using probabilistic sensitivity analysis approaches [ 26].
Simulation results indicated that all of the vaccination strategies considered in this paper were sufficient to eliminate VT transmission in England and Wales with base case values for vaccination coverage and other parameters.
Varying the rate of change in regimen between 50% and 150% of base case values (for all arms simultaneously) had little effect on the ICER for viral load ($4882-5466 4882-5466
Based on these model estimates (see appendix), we applied the following base case values for condom usage following the intervention: 53.2% for the control group, 57.7% for the complete intervention, and 56.8% for the condom use skills component.
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AKI-associated in-hospital costs were calculated for 2013 according to DRG-related calculation for single diagnosis/ procedure and adjusted to nationwide base case value for reimbursement.
The argument so far has relied on a base case value for cV (=0.4) grounded in a study of preventable adverse events.
Table 2 reports an example of calculation of External Costs choosing as parameters, respectively: year 2000, base case value for the IQloss- Pbblood slope, discount rate of 3%, and damage window for Pb impacts of 3 years from birth (0
For BMS, an average 12-month TLR rate of 16.3 % was calculated across all three studies to serve as the base case value for BMS as a class (Table 2).
The coefficient of variation of the overall mortality rate (cM) for 143 Acute Hospital Trusts in England in 2007/8 was 0.19; 23 here a base case value for cM of 0.2 has been assumed.
The base case value for each parameter was varied from the default value within reasonable lower and upper limits as defined in the published literature and by expert consultation, with variations of ±50% applied to parameters for which no ranges were identified in the literature.
Gas-phase oxidation does not appreciably affect the droplet lifetime, for the selected base case values of the above parameters, because droplet heating is controlled primarily by the liquid-phase decomposition.
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