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Our analysis of the reasons behind the exclusion of false negative cases by the base case suggests that some of these cases may be atypical presentations of fall-related incident hip fractures, such as elective admissions rather than being admitted as an emergency case or hip operation procedure(s) not being performed due to patients' frailty or a terminal illness.
If the model had assumed that the frequency of sexual activity remained unchanged after the introduction of condom distribution in correctional settings, as several reports in the literature suggest [ 7, 19, 20], our model would have predicted even greater reductions in transmission than our base case suggests.
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This represents a savings of $1.55 million relative to the original base case, suggesting that with the crude assumptions employed here, an escort vessel is well worth the money even in the absence of EP.
Finally, the sensitivity analysis found that the inclusion of interhospital transfers (S1) did not alter the accuracy of the base case, suggesting that transfers may be counted as incident cases.
32, 34 The key sensitivity analyses resulted in ICERs that were similar to the base case, suggesting robustness of the model's results regarding the economic benefits of pregabalin.
The inclusion of cases irrespective of whether or not they had the same first-listed external cause codes as the preceding fall-related hip fracture (S7) resulted in accuracy estimates being identical or near identical to those in the base case, suggesting that this criterion was not a key driver of accuracy.
Strategy 4 in fact now gives the greatest INHB at a willingness-to-pay of £20,000 per QALY (129.0 QALYs), although this is still lower than the INHB of Strategy 5 in the base case, which suggests that methylation testing may not be as cost-effective as BRAF testing, although the difference (if there is one) is likely to be small.
For patients with two organ systems failing, the results are less clear; whereas the base case finding suggested that DrotAA was not cost-effective, the sensitivity analysis suggested that the intervention was cost-effective if limited to those patients who received DrotAA within 24 hours.
While in this analysis the point estimate for cost effectiveness suggested "dominance" of larval therapy that is, larval therapy being better and cheaper than hydrogel the uncertainty associated with this result was consistent with the base case analysis suggesting no difference between larval therapy and hydrogel in terms of health benefits or costs.
Another case suggests so.
The Proctor case suggests why.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com