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The top line shows the base case result and represents the scenario of aspirin resulting in a 50% reduction in 5 year cumulative EAC incidence.
Sensitivity analyses confirmed the base case result to be robust.
We found that accounting for future costs did not significantly alter the base case result.
The base case result was not sensitive to the discount rate (see Table 6).
The base case result of ICER 1,124 Int$/LYG is highly cost-effective in our local context.
The base case result was not sensitive to alternative data and methodology but considerably affected by sustainability assumptions.
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Base case results show that the combined system costs are higher than those of the individual systems.
Increasing this cost from 10 to 30 USD/ton for the base case results in increasing the ethanol costs from 0.91 to 1.42 USD/L.
Supplementary studies were used to define a knocked-down stress strain curve, and to show that using base case results is conservative for more complex situations.
The probabilistic sensitivity analysis performed in addition substantiated the validity of the favorable base case results.
In two-way sensitivity analysis, we modeled the base case results plus clinical benefits from universal HAART access for clinically-indicated HIV infections (but ignoring the added costs of HAART).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com