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Finally, when we reduced the mean age of the cohort but maintained the base case prevalence, one-time routine HIV screening became more cost-effective.
We considered this latter figure to be a more realistic estimate of the prevalence of CD and, therefore, adopted this figure for our base case prevalence assumption; 23,037 patients were used as the upper limit of the range (Ipsen Biopharm Ltd ,unpublished data, October 2012).
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Figure 2 provides a graphical representation of the incremental cost-effectiveness of these screening strategies.> -wrap-foot> Assessed for base-case: prevalence of CIN 2/3 and cervical cancer (CC) was 1.3%.
One-way sensitivity analyses applied to the base case showed that the prevalence of CD; dose per injection of onabotulinumtoxinA, incobotulinumtoxinA, and abobotulinumtoxinA; and time to reinjection of incobotulinumtoxinA and abobotulinumtoxinA were the most influential parameters on net budget impact.
In the base case scenario, HAE-C1-INH prevalence is 2 per 100,000 persons and each patient suffers an average of 6 acute attacks per year.
An Allied Health Assistant AHAA) was designated as group instructor in the base case analysis due to their prevalence in Australian healthcare settings.
While clinical signs (head nodding) of Nodding syndrome are distinct and readily recognised, the diagnostic criteria used by the Ugandan Ministry of Health (MOH) between 1998 and 2011 appear to have overestimated case prevalence twofold based on the current MOH-Centers for Disease Control CDCcasease definition.
The ART-adjusted estimate is higher than the base case because there is a higher prevalence of CIN3 in ART-naïve women (Table 2) and a higher proportion of ART-naïve women from the Spectrum model than in our cross-sectional study in Lusaka.
Two scenarios (upper and lower bounds of base case) represented plausible variants, assuming different rates of treatment prevalence and intensity.
All the percentage reductions in MRSA infection prevalence shown in this figure were computed relative to a base case corresponding to no hygiene prevention measures in place.
Each percentage reduction in MRSA infection prevalence shown in this figure was computed relative to a corresponding base case without vaccination.
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