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The base case indicates societal cost savings over the next 32 years of $74,777 (Table 3).
Our base case indicates that $US1545 per PN patient may be saved; even if as few as 50% of PN patients are candidates for standardized pre-mix formulations, a potential savings of $US773 per patient may be realized.
The base case indicates that $US1545 per PN patient can be saved (PN costs and BSI cost avoidance) if all PN patients are appropriate candidates to receive PN via MCB.
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The results of electrochemical impedance spectroscopy (EIS) show that the charge transfer resistance for the fuel cell with twice the thickness of CCL is 30% lower compared to that for the base case, indicating that the active catalyst area available for oxygen reduction reaction (ORR) is indeed greater.
Overall, the costs predicted by the sensitivity analyses were much higher than the base case, indicating an underestimation of true costs.
Results from this "real-world" scenario were broadly similar to those in the base case, indicating that the use of BoNT-As could lead to significant budgetary savings.
Our base case analysis indicates that, compared with hydrogel, larval therapy confers a small health benefit for people with leg ulcers, as measured by QALYs and time to healing, at a minor additional cost to the UK NHS.
Base case analysis indicates that the incremental cost of IGRA alone is offset by the increased effectiveness of this approach over the two-stage sequential approach of TST followed by IGRA for positive TST results (table 3a).
Sensitivity analysis of the base case model indicates that the ICER for IGRA ranges from £20 929 to £10 614 per healthy life year gained for test specificities of 97%–99% (figure 2A C, supplementary table 2).
Modeling using the base case parameters indicates that condom distribution in a segregated MSM unit at the Los Angeles County Men's Jail is a cost-saving intervention (that is, intervention costs are more than offset by future HIV/AIDS-related medical care costs avoided) when condoms are used 51%% of the time.
The inducible expression cassette in the pTcINDEX vector contains a tetracycline-dependent T7 promoter, with the tet operator sequence (tetO, cCTATCAgTGATAGa, where upper case indicates bases important in tetR binding) placed immediately downstream.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com