The prices were deflated or inflated to year 2000, the base case for the analysis, by applying consumer price indices (CPI) from central-bank or similar government agency web-sites, or CPIs from international organizations when the central bank did not report them.
The incremental cost-effectiveness ratio for the base case analysis for white males was $87,792.
For the base case analysis for the COPD management cost, the all-cause medical costs were used.
In addition, we performed sensitivity analyses on lower and higher values than the base case analysis for fatal complication rates with colonoscopy and for unit costs of FIT, colonoscopy, complications and treatment.
This scenario analysis (Table 9) showed the dominance of escitalopram versus the other antidepressants, as also seen in the base case analysis for Veneto.
In the sensitivity analyses we compared all policy-strategy combinations simulated in the base case analysis for five different scenarios that represent contrasting real life situations (table 3).
Similarly, the mean number of days on study drug from the PLATO trial was not used; instead, 365 days of treatment was assumed in the base case analysis for patients who did not have a fatal event in year 1.
Based on the striking difference between risk and non-risk groups, and the additional uncertainty about the contribution of Streptococcus pneumoniae to non-bacteraemic pneumonia, particularly in high risk children, we decided not to include an overall impact on non-bacteraemic pneumonia in the base case analysis for the high risk groups.
Linear elastic-base case For the time-history analysis of elastic-base case, the FootingCondition 3 is used.
Point estimates for these odds ratios were used for our base case analysis, with 95% confidence intervals used for sensitivity analysis, using the procedures discussed below.
