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Exact(4)
Table A of the appendix (online) presents the corresponding percentage change over the base case estimates for other scenarios.
Figure 4 shows the results of the one-way sensitivity analysis used to construct the ranges around the base case estimates for the inflated scenario (Table 3).
The base case estimates for probability of achieving an improved HDDS or FCS outcome were taken from the LIG survey [ 20].
Base case estimates for both 6 and 8 years demonstrated that cost-effectiveness improved as the time horizon lengthens with £13,626 (€21,840) and £11,000 (€17,631) cost per relapse avoided respectively.
Similar(56)
The base case estimate for the utility associated with this state assumes life-long sequelae [ 13].
The base case estimates of the cost per QALY averted for the complete intervention and the condom use skills component fell below this $50,000 threshold.
Combined incremental variation of treatment time (to 10 minutes), capacity utilization (to 125%) and linear accelerator staff numbers (to 3) resulted in a decrease in the base case estimate of total costs for long-course radiotherapy (25 fractions) of 35%, from €3,609 to €2,354.
As such, base-case estimates for BCHD costs per patient were based on current staff, drug, and diagnostic expenditures for an average active TB case; uncomplicated active TB cases were assumed to require only outpatient treatment with no hospital days.
Mean total payment per RBC transfusion episode was higher than base-case estimates (Table 2) for patients with cancer or blood disease (mean, $969; SD, $1,948) and lower than base-case estimates for patients with an acute bleed or surgery (mean, $733; SD, $1,195).
In all of the sensitivity analyses for restricted activity days and asthma symptom days, point estimates fell within the 95% confidence intervals on the base case estimates.
Our base-case estimate for TPV/r may thus well be acceptable in the Dutch context.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com