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The base case estimate for the utility associated with this state assumes life-long sequelae [ 13].
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Table A of the appendix (online) presents the corresponding percentage change over the base case estimates for other scenarios.
The base case estimates for probability of achieving an improved HDDS or FCS outcome were taken from the LIG survey [ 20].
Base case estimates for both 6 and 8 years demonstrated that cost-effectiveness improved as the time horizon lengthens with £13,626 (€21,840) and £11,000 (€17,631) cost per relapse avoided respectively.
Figure 4 shows the results of the one-way sensitivity analysis used to construct the ranges around the base case estimates for the inflated scenario (Table 3).
Combined incremental variation of treatment time (to 10 minutes), capacity utilization (to 125%) and linear accelerator staff numbers (to 3) resulted in a decrease in the base case estimate of total costs for long-course radiotherapy (25 fractions) of 35%, from €3,609 to €2,354.
The base case estimates of the cost per QALY averted for the complete intervention and the condom use skills component fell below this $50,000 threshold.
Our base-case estimate for TPV/r may thus well be acceptable in the Dutch context.
The base-case estimate for the cost of training per NASG use was $1.62.
For the first, we replaced our base-case estimate for diabetes risk reduction (55.3%) with the estimate of 38.0% from the 10-year DPP follow-up (35).
However, neither the length of ICU stay nor the associated cost of ICU affected the cost saving found in the base-case estimate for the E-vita open plus in the long-term.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com