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The base case analysis showed that BUCCOLAM dominated current care, rectal diazepam and unlicensed buccal midazolam in all countries.
Base case analysis showed that the estimated QALY gain per patient was highest with celecoxib plus PPI (0.40) followed by etoricoxib plus PPI (0.38) and celecoxib alone (0.37) versus all comparators.
The base case analysis showed that when Mydriasert substituted mydriatic eye drops, annual total costs decreased by 18%%, saving £2111 £1.200 per patient) (Table 2; Fig. 3).
The base case analysis showed that when Aprokam replaced purchased PFS, the overall total cost over 5 years was reduced by 4.8%% (total cost: £69,052 with Aprokam and £72,541 with purchased PFS) (Table 4).
The base case analysis showed that patients treated with tiotropium gained 0.07 quality-adjusted life years (QALYs) compared to usual care alone at an incremental cost of SEK 15,041, resulting in a cost per QALY gained of SEK 224,850.
The results of the base case analysis showed that in Europe, assuming a theoretical mean cumulative vaccination coverage rate of 70%, the introduction of a girls-only vaccination strategy was associated with a notable reduction in the incidence of HPV-related diseases in both males and females in comparison with screening alone (Table 4).
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The results of the base case analysis show that hysterectomy is the preferred strategy as the first intervention for heavy menstrual bleeding.
Thus, dividing 1,295,126 units saved by 33 uniTSAC theC, the base-case analysis showed that 39,246 TSACs could potentially be avoided annually in the US ICUs, with the cost savings of $821,109,826.
In Spain, the base-case analysis showed an ICER for LMP compared with gabapentin and pregabalin of €7,009 and €4,230 per QALY gained respectively 54 Scenario analysis with a lower LMP consumption of 1.1 per day showed the ICER decreased to €3,525 per QALY gained compared with gabapentin and to €742 per QALY gained relative to pregabalin.
Generally the complete case analysis showed similar results to the results based on the imputed datasets.
The assumptions made in the base case analysis are shown in Table 6.> Uncertainty was assessed both through deterministic and probabilistic sensitivity analysis (PSA).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com