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The base case analysis estimated the relative efficacy of the interventions of interest with the maximum dose allowed in OA.
Our base case analysis estimated the total gain at about 0.11 QALYs between screening and no screening (table 4).
The base case analysis estimated the ICURs between the strategies using point estimates of the parameters (i.e., weighted-average from the meta-analysis).
As a result, this base case analysis estimated the potential budget impact of shifting the number of prescriptions filled by one product, while keeping the proportion of product prescriptions according to dose strength and their daily average number of doses constant.
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Base-case analysis estimated the total direct and indirect cost of treating patients with BC in the United States at $589 millionn.
Within a cost utility framework, the base-case analysis estimated the incremental healthcare cost per additional quality-adjusted life year (QALY), using the EQ-5D to generate QALYs, for each risk-defined subgroup.
In the base case analysis, the estimated odds ratio was 0.32 (0.13,0.76) for the randomised studies alone and 0.57 (0.41,0.82) for the non-randomised studies alone.
The incremental cost effectiveness ratio for the base case analysis was estimated at £8826 per QALY gained and £40 per ulcer-free day.
Although the WINGS intervention (particularly the condom use skills component) appeared to be cost-effective in the base case analysis, the estimated cost-effectiveness of the WINGS intervention is less favourable than that of two other small group HIV prevention programs for at risk women [ 13, 35].
The base case analysis resulted in an estimated cost-effectiveness ratio of £1730/QALY gained from BA compared with usual care.
We used the WAC for the base case analysis as our best estimate of the cost that most hospitals pay for inpatient medication.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com