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In the base case analyses of these studies, cost-effectiveness results ranged from dominated to dominant.
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The base-case analyses of a 65-year-old person with a CHADS2 score >1 gained 0.17 and 0.21 quality-adjusted life years over warfarin for 30 mg od and 60 mg od edoxaban, respectively.
For the base case analyses, the cost of a false negative (pre-diabetes or diabetes that was undetected) was evaluated as 10% of the projected marginal 3-year medical costs for that condition, assuming that marginal costs could be decreased by appropriate management, as they were in the Diabetes Prevention Program DPPP) (16, 17).
These analyses were carried out using the base probability and utility values in the model, with the incidence of SCID among newborns set to 0. Outcomes measured in base case analyses were the number of TB cases occurring (meningeal, miliary, and other), and quality-adjusted life years (QALYs) in each cohort.
In our base case analyses, we assumed that the degree of clustering of HPV related tumours in men who have sex with men is determined by the prevalence of such men in the population and their relative risks of HPV associated cancers irrespective of aetiology.
Base case analyses investigated the cost effectiveness of more than 1500 different screening policies using the microsimulation model.
The base case analyses were performed using 200 replications of 100,000 simulated patients.
Similarly, inclusion of just incident users (first PPI prescription within 90 days) confirmed the results of the base case analyses.
According to these base case analyses, the incremental total cost difference of erlotinib vs docetaxel amounts to −€1577.
As shown in Figure 2, the sensitivity analysis results confirm the robustness of the "base case" analyses results.
Sensitivity analyses were conducted for the base case analyses.
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