Sentence examples for basal patterns of gene from inspiring English sources
The COMPARE program of the NCI Developmental Therapeutics Program was used to examine the correlation between the LMR-12 staining results and sensitivity for compounds tested, and with basal patterns of gene expression in the 55 cell lines measured by cDNA microarray.
However, comparison of 12-week-old and 12-month-old mice revealed that age affects the basal pattern of gene expression in joint tissues [ 29], and when DMM is performed on 12-month-old animals, the ensuing OA is more severe than in young mice [ 29].
Olopade and Grushko [ 42] suggest that tumors with BRCA1 mutations may be consistent with a basal-like pattern of gene expression because six out of seven tumors from patients with BRCA1 mutations stained positive for basal keratins and none showed ERBB2 overexpression.
Gene set enrichment analysis (GSEA) revealed exclusive enrichment patterns of gene signatures related to basal (mammary basal cell signature and p63 pathway, Fig.1d) and luminal (mammary luminal cell signature and AR pathway, Fig. 1e) epithelial phenotypes, respectively.
We further examined the correlation between HIF-1α expression and both hypoxia-related gene expression and basal-like gene expression across both the primary and validation dataset and demonstrated a significant (P <0.0001) relationship between both patterns of gene expression.
Analysis of the basal gene expression patterns of renal genes throughout the life cycle of the rat will improve the use of current and future renal biomarkers and inform our assessments of kidney injury and disease.
Recently it was demonstrated that the expression patterns of genes mediating DV patterning in early development are highly conserved between basal chordates (cephalochordate amphioxus) and vertebrates [2].
We noted a basal expression pattern of both genes in the young root tip, including the susceptible zone and did not observe a discernible change in expression pattern of neither MtCCD7 nor MtCCD8 following LCO treatment (Additional file 4).
